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Furthermore, systematic optimization of stimulation protocols, regarding stimulation intensity, duration, repetition rate, targeting, electrode arrangement, and computational modeling based on individual MRI scans to optimize stimulation protocols at the level of the individual might be helpful to increase efficacy of the intervention [243, 244]

10.1038/s41569-018-0030-z Summary Keywords D-Gal, endothelial cell senescence, FOXO4-DRI, P53, ROS Citation Hu Z, Li F, Hu C, Shan Q, Tang Z, Jiang M, Yi X, Chen X, Jin L, Wang X and Wang Y (2026) FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway

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