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GLP-1s slow down digestion, so big meals can sit heavy in the stomach and trigger nausea

According to the Rybelsus SmPC (available on the Electronic Medicines Compendium) and the EMA's European Public Assessment Report (EPAR), oral semaglutide uses a proprietary absorption enhancer called SNAC (sodium N-[8-(2-hydroxybenzoyl) aminocaprylate]) to facilitate absorption through the gastric mucosa

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