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doi: 10.1093/ajcn/nqaa049 309

5 Thymidylate Synthase inhibition specifically increases mitochondrial mass in an mTOR dependent manner

9 Conclusions Breast cancer until today remains a significant global health threat characterized by multifaceted and complex etiology and diverse clinical presentation

Calculations of key parameters of the mitochondrial function were performed, consisting of basal respiration (BR, OCR initial OCR rot/AA ), ATP production (ATP, OCR initial - OCR oligo ), proton leak (PL, OCR oligo OCR rot/AA ), maximal respiration (MR, OCR FCCP OCR rot/AA ), spare respiratory capacity (SRC, OCR FCCP - OCR initial ), spare respiratory capacity [%] (SRCP, MR/BR*100), non-mitochondrial respiration rate (NMRR, OCR rot/AA ), and coupling efficiency [%] (CE, ATP/BR*100)

Outcomes include heightened energy, bolstered immunity, and an even complexion