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At a glance GLP-1 medicines such as Ozempic, Wegovy, and Mounjaro do far more than help with weight loss

[DOI] [PubMed] [Google Scholar] 81.Donini L.M., Busetto L., Bischoff S.C., Cederholm T., Ballesteros-Pomar M.D., Batsis J.A., Bauer J.M., Boirie Y., Cruz-Jentoft A.J., Dicker D., et al

At 5 mg/mL: 50 units = 2.5 mg This is the lowest concentration commonly available

GLP-1 receptor agonists pass the bloodbrain barrier and directly engage with GLP-1 receptors in essential appetite-regulating sites of the hypothalamus and brainstem (Trapp and Brierley 2022)

Semaglutide with B12 versus semaglutide with niacinamide Some pharmacies compound semaglutide with niacinamide (vitamin B3) instead of or in addition to B12

Whilst Ozempic has demonstrated significant benefits in improving HbA1c levels, with weight reduction as a secondary effect, it is important to note that it is not licensed for weight management in the UK