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Data from the Danish DANHEP registry similarly demonstrated that CHB patients with cardiometabolic disorders experience higher rates of early liver complications compared with those without such conditions, underscoring the substantial burden of metabolic comorbidity in European HBV populations (95)

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Therefore, the National Bone Health Alliance recommends that parameters of bone strength (such as changes of cortical pore and trabecular microstructure in bone) should be used to diagnose osteoporosis in T2DM

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