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Long-term use of metformin, proton pump inhibitors or H2 blockers , which can reduce B12 absorption over years

By blocking NNMT, the compound is associated with preserved NAD+ levels and reduced fat storage, alongside improvements in cellular energy utilization and insulin sensitivity

Lu H, et al

The following groups of people are at a greater risk of developing a vitamin B12 deficiency: Vegans or vegetarians People 75+ years Having a digestive system disorder like Crohns or celiac disease Drinking excessive amounts of alcohol Having Sjgrens syndrome Taking certain medications like oral birth control or metformin Common symptoms of a vitamin deficiency include fatigue, numbness, poor balance, memory loss, and breathlessness

Excellent product Have been using this for while and the energy improvement has been phenomenal

Clinical studies tested doses ranging from 250mcg to 1mg daily, with 300mcg showing effective fat reduction at the lowest side effect profile