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This research was supported by National Natural Science Foundation of China (82271112)

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Nitric oxide and neurological disorders

Stacking them could amplify GH and IGF-1 elevation beyond intended levels, increasing the risk of side effects including fluid retention and potential IGF-1-driven proliferative effects

Only 11.2% of participants stopped the trial due to side effects, and the discontinuation rate dropped significantly after week 24, suggesting those who make it through the early phase generally tolerate it well long-term