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The Nutritional Gap Challenge A 2025 study published in ScienceDirect found that over 20% of people starting GLP-1 therapy had nutritional deficiencies diagnosed within the first year

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Researchers found its safety profile was virtually identical to placebo, with no treatment-related serious adverse events reported in any study

But adding tesamorelin growth hormone elevation to retatrutide metabolic milieu creates an interaction that has never been studied

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