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This may suggest that the reduction in free estrogen levels is a result of increased sulphate and glucuronide conjugation or increased oxidation via the estrogen biotransformation pathway

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It has a strong evidence base but can cause irritation or unwanted hair growth in some people, and must be used continuously to maintain benefits

2024;5(10):e718

DSIP and its analogues: potential neuroprotective research applications

In adipose tissue, the combination of GIP-mediated fat cell signaling with GLP-1-mediated appetite suppression appears to produce metabolic improvements through complementary mechanisms reducing energy intake while simultaneously improving adipose tissue insulin sensitivity