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Oxidative stress is widely considered a key driver to its pathogenesis

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PMID 17584759

Cartilage, less essential for survival, may not fare well under conditions of sulfur deprivation, explaining why dietary supplements containing sulfur (chondroitin sulfate, glucosamine sulfate, MSM (Methylsulfonylmethane), etc.) may be of benefit in the treatment of joint diseases [20]

More research is needed to confirm lavender essential oil's effects when used in aromatherapy

Though the regulatory agency generally does accept the determinations of panels like these, it can and has rejected panel votes in the past