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TMEM16A is frequently overexpressed in epithelial cancers and contributes to multiple biological functions of cancer cells (345)

Clin Sci (Lond) (2007) 113(4):20512

Other causes include gastrectomy, Crohn's disease, celiac disease, bariatric surgery, and chronic use of certain medications, such as proton pump inhibitors (PPIs) and metformin

Our approach is thorough but practical

Real-world outcomes from compounding pharmacies show that individual results range from 5% to 25% body weight loss depending on starting weight, adherence, and genetic factors

Because it is a naturally occurring compound involved in energy metabolism, adverse effects are rare