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The connection between liver fat reduction and decreased insulin, C-peptide, triglycerides, and increased adiponectin suggests there is a wider metabolic benefit, not just localized liver effects

These medicines mimic the action of a naturally occurring hormone called GLP-1, which is produced in the intestines in response to food intake

By stopping this, the MASLD may be prevented or alleviated if it already exists

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However, the emergence of retatrutide has introduced a "ceiling-breaking" potential that is difficult to ignore

doi: 10.3390/ijerph18115533