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Immunity 31 , 245258 (2009)

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In the MCT-induced PAH rat model, Blueberry Extract can reduce total reactive oxygen species (ROS), NADPH oxidase activity and lipid oxidation in lung tissues, restore the expression of transcription factor Nrf2, activate downstream antioxidant enzymes, and at the same time correct the balance of endothelin receptors, reducing ET-1-mediated inflammatory vascular remodeling (Turck et al., 2020