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Furthermore, it has been reported that PGC-1 may also inhibit rotenone-induced dopaminergic neurotoxicity by regulating the dynamic balance of mitochondrial fission and fusion proteins and determining the structure of the mitochondrial network (Peng et al., 2017)

Leptin mimetics To overcome leptin resistance (Fig

Probiotic supplementation can upregulate butyrate and modulate dopamine D2 receptor expression, improving social deficits in mouse models (Chen et al., 2024

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