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& Devos, P

While cumulative evidence has demonstrated that mitochondrial metabolism reprogramming plays crucial roles in the promotion of cancer progression, the molecular mechanisms underlying the alterations of mitochondrial metabolism in cancer cells remain incompletely understood

Protein intake is crucial during management to maintain muscle mass so that the observed loss corresponds to a normal readjustment of it in relation to body weight

However, it requires careful handling

In a phase 2 clinical trial conducted on an obese population, over a 26-week period, patients who were administered a dose range of efinopegdutide from 5 mg to 10 mg experienced a weight reduction of up to 11.8%

Over the years, several anti-obesity drugs have been used to support nutritional therapy in patients with PWS [31, 49]