doi: 10.1016/S0002-9440(10)63536-5 11 ClarkeLEFlakeDD2ndBusamKCockerellCHelmKMcNiffJet al
His/His SULT1A1 eliminates the sulfation backup for catechol estrogens, increasing quinone formation risk in parallel with slow COMT
FDA-APPROVED INDICATIONS Injection Weight loss (adults) As an adjunct to diet and exercise for weight loss in adults with a BMI 30 or 27 in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes, dyslipidemia) [STEP 1 study] Adult BMI calculator Weight loss (children 12 years old) As an adjunct to a reduced-calorie diet and increased physical activity in pediatric patients aged 12 years and older with an initial BMI at the 95th percentile or greater for age and sex
In an ideal world, this yin and yang work together beautifully
For instance, the suggested improvement of metabolism by L-carnitine supplements is based primarily on short-term supplementation (125)
Prompt treatment is essential, as neurological damage may become irreversible if treatment is delayed
