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Gastrointestinal issues : Conditions like celiac disease or Crohn's disease can impair B12 absorption in the gut

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Thus, another aspect for future research of Se at the brain barriers may be related to improving our understanding on sex-related differences, including the effects of dietary Se, selenoproteins, and selenometabolites on permeability and function of BBB, BCB as well as gut-brain axis and brain immunity

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