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Limited long-term safety data

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In chronic liver disease, this could be expressed through significant reduction of clinical outcomes such as the development of cirrhosis and its complications (ascites, hepatic encephalopathy, gastrointestinal hemorrhage), as well as all-cause mortality 7

And so, what I would say is they haven't seen a lot of evidence by December that inflation's coming back down, and the labor market has stabilized

5 CRS and biomarkers 5.1 Existing biomarkers in CRS The initial definition of CRS was that it is the outcome of interactions between the renal and other circulatory compartments that increased circulating volume, exacerbated symptoms, and disease progression of patients with HF (Rangaswami et al., 2019)