Increased levels of NAPQI reduce the ability to detoxify a host of toxic chemicals in the environment, increasing oxidative stress, which leads to protein, lipid, and nucleic acid damage from free radicals
Offermanns, S
The recommended dosage varies based on individual needs, but a general range for oral supplementation is between 250 to 1,000 mg per day
Meissner WG, Remy P, Giordana C, Maltete D, Derkinderen P, Houeto JL, Anheim M, Benatru I, Boraud T, Brefel-Courbon C, Carriere N, Catala H, Colin O, Corvol JC, Damier P, Dellapina E, Devos D, Drapier S, Fabbri M, Ferrier V, Foubert-Samier A, Frismand-Kryloff S, Georget A, Germain C, Grimaldi S, Hardy C, Hopes L, Krystkowiak P, Laurens B, Lefaucheur R, Mariani LL, Marques A, Marse C, Ory-Magne F, Rigalleau V, Salhi H, Saubion A, Stott SRW, Thalamas C, Thiriez C, Tir M, Wyse RK, Benard A, Rascol O, Group LS (2024) Trial of Lixisenatide in early Parkinsons disease
Others havent covered these drugs yet, but theyre hearing about it from employees and starting to factor GLP-1 coverage into their hiring decisions
For young, otherwise healthy individuals taking the drug solely for weight loss, the equation is less clear, and a frank discussion with a physician about absolute versus relative risk is warranted
