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Functional peptides were only verified in non-human primates, whereas in all other mammals the truncated -defensin precursors have additional premature stop codons and are pseudogenes [127, 128]
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Key Takeaways ARA-290 (cibinetide) is derived from erythropoietin without erythropoietic effects It activates the innate repair receptor It reduces inflammation while preserving immune function It supports nerve repair and tissue protection It has been studied extensively in neuropathic and inflammatory conditions It fits naturally into an integrative medicine framework The Bigger Picture ARA-290 represents a shift away from symptom-focused medicine toward cellular repair biology
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