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Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2-mediated stress signaling

Scores of 1 or 2 indicate less diversity than the defined normobiotic reference population

Since our proteomic study suggested mitochondrial alterations following HC treatment, and considering the recent hypothesis of Simeone (Simeone, 2025) that HC might interact with key cellular antioxidant systems, mitochondrial function was further investigated through oxygen consumption rate (OCR), extracellular acidification rate (ECAR), mitochondrial membrane potential, mitochondrial network morphology, ROS production and GSH/GSSG ratio

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Liraglutide is administered as a once-daily injection