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After intramuscular administration, these testosterone esters are absorbed gradually from the muscle and then enzymatically cleaved to release free testosterone

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Additionally, losing lean mass can make it more difficult to maintain weight loss over the long term (2)

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The headline weight-loss numbers Analyzed by planned treatment, mean body-weight change from baseline to week 46 was dose-dependent: about 6.2% at 0.6 mg, 12.5% at 2.4 mg, 13.2% at 3.6 mg, and 14.9% at the top 4.8 mg dose, compared with roughly 2.8% for placebo