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Combining topical application at the wound site with systemic injection represents a comprehensive approach for significant wounds

doi: 10.1002/jnr.22565 74 PellecchiaMTPivonelloRLongoKManfrediMTessitoreAAmboniMet al

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402 designed a dual-targeting drug delivery system for miR-21 inhibitors, consisting of a PDL1-binding peptide covalently linked with an anti-miR-21 inhibitor via a click reaction

The steady-state plasma concentrations of fluoxetine and norfluoxetine increased by about 18% and 36%, respectively, and concentrations of paroxetine decreased by about 27%

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