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In Phase 1 and 2a clinical trials, once-daily subcutaneous injections of RG7697 (0.252.5 mg) for 14 days in 56 patients with T2DM and 1.8 mg of RG7697 for 12 weeks in patients with T2DM who were poorly responsive to metformin reduced body weight and improved glycemic control

H., Lim, A

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Nevertheless, the relatively short duration of follow-up remains a major limitation because the time required for PDAC to emerge from a normal cell is estimated to be greater than 10 years 31

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