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doi:10.1182/blood.V93.6.1798.406k22_1798_1808

Even when lab values appear normal on medication, many patients still struggle with: Slowed metabolism Insulin resistance Increased fat storage Chronic inflammation Fatigue that limits physical activity These factors create a perfect storm where calorie restriction backfires, muscle mass declines, and weight loss stalls

Some studies suggest it may influence pigmentation pathways indirectly by reducing oxidative stress and inflammatory signalling

Jiang X, Li Y, Fu D, You T, Wu S, Xin J, et al

The movement for more diverse representation in media reminds us that all skin tones deserve visibility and recognition