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The first is DF, a carbohydrate polymer derived from bacterial cell walls that cannot be hydrolyzed by enzymes in the small intestine, which exerts complementary or overlapping functions with prebiotics

Shahid, A

The SEMALEAN study, published in 2025, tracked 115 semaglutide patients over 12 months using DEXA scans and found that while total lean mass initially declined, it stabilized by month 12 while fat mass continued dropping throughout

Am J Clin Nutr 1997, 66: 760-773

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Unfolded protein response A cellular stress response activated by the accumulation of unfolded or misfolded proteins in the endoplasmic reticulum, aiming to restore normal function