Yang C, Ko B, Hensley CT, Jiang L, Wasti AT, Kim J, et al
Lipofuscin accumulates extensively in RPE cells, and its toxicity is determined by the total content of its main fluorescent group, N-subretinoyl-N-retinol-ethanolamine (A2E)
Based on molecular characterization of tumor cells, it is becoming increasingly evident that patient subgroups harbouring certain genetic mutations or overexpressing certain proteins may be particularly susceptible to benefiting from VitC mono- and combination therapies
All this information that is being generated on the molecular and pharmacodynamic mechanisms leads us to see the need to create multidisciplinary investigative groups for the development of hepatoprotectors or hepatic antioxidants
Derbyshire SW, Vogt BA, Jones AK (1998)
Weight & obesity Investigated in animal models of diet-induced obesity