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The American Society of Anesthesiologists (ASA) has provided guidance on GLP-1-RA use prior to surgery based on the pharmacological half-life, advising that daily medications should be held a day before surgery, and weekly GLP-1-RA should be held a week before surgery

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The peptide wolverine stack is an informal term used by research communities

Whilst the use of DPP-4 inhibitors may theoretically support weight loss in the treatment of obesity through increasing the half-life of endogenous GLP-1, weight loss associated with their use is clinically insignificant (0.160.64 kg) [29], and as such their use in obesity is not explored further in this manuscript

Nutrition & Metabolism,17 , 80

Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation