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IP3 encourages the release of Ca from intracellular stores, increasing the cytosolic calcium concentration, while DAG activates protein kinase C (PKC)

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Front Pharmacol 13:933998 Fataki MR, Kisenge RR, Sudfeld CR, Aboud S, Okuma J, Mehta S, Spiegelman D, Fawzi WW (2014) Effect of zinc supplementation on duration of hospitalization in Tanzanian children presenting with acute pneumonia