This study aims to pinpoint genetic causes of ME/CFS by testing more than 25,000 DNA samples (586), as a large cohort will help achieve statistical power with reproducible and rigorous results (52)
Neumann, I
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Bcl-2: B-cell lymphoma 2, Bcl-XL: B-cell lymphoma-extra large, cAMP: cyclic adenosine monophosphate, CREB: cAMP-response element-binding protein, FoxO1/O3: forkhead box transcription factor 1/3, GLP1R: glucagon-like peptide-1 receptor, GSK-3: glycogen synthase kinase-3, LTP: long-term potentiation, MAPK: mitogen-activated protein kinase, mTOR: mammalian target of rapamycin, NF-B: nuclear factor kappa B, PD: Parkinsons disease, PI3K: phosphoinositide 3-kinase, PKA: protein kinase A
Researchers did not have information on other factors that could affect the risk of epilepsy, such as family history, genetic susceptibility or alcohol use
