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The American Cancer Society notes that elevated circulating IGF-1 is associated with increased risk of colorectal, breast, and prostate cancers, though causality versus correlation remains debated

Instead, they are offered as one component of a comprehensive wellness strategy, which may include: Nutritional counseling Lifestyle coaching wellness monitoring personalized health planning Our goal is to help patients feel supported as they work toward their personal health and wellness objectives

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But in practice, normal plasma L-Arginine levels already exceed the concentration eNOS needs to function, so adding more should theoretically have no effect

Maintenance sessions may be recommended to sustain optimal results.