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(106) included seven randomized, placebo-controlled trials that exclusively enrolled individuals with high blood pressure, i.e., with systolic blood pressure (SBP) 140 mm Hg and/or diastolic blood pressure (DBP) 90 mm Hg

7.1 pH) and washed with mitochondrial respiration medium MiRO5Cr (EGTA (0.5 mM), MgCl 2 (3 mM), lactobionic acid (60 mM), taurine (20 mM), potassium dihydrogen phosphate (10 mM), HEPES (20 mM), d-sucrose (110 mM), BSA fatty-acid-free (0.1%) and supplemented with creatine (20 mM) right before use) before homogenization

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In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)