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Numerous studies have investigated the expression patterns of endogenous GLP-1 and GLP-1R in the central nervous system (CNS) and the peripheral nervous system, with a consensus that these are expressed on neurons and found in most areas of the brain and gutbrain axis 2

Pay attention to your symptoms and ask your clinician for personal advice

Dimples or depressions at previous injection sites indicate lipoatrophy

Hryciw DH, Patten RK, Rodgers RJ, Proietto J, Hutchinson DS, McAinch AJ (2024) GPR119 agonists for type 2 diabetes: past failures and future hopes for preclinical and early phase candidates

Check Your Eligibility If you want to learn whether GLP-1 treatment is right for you and receive personalized guidance from providers who understand how to optimize your experience, you can start by completing Mochi's eligibility questionnaire

GDMT for HFrEF typically includes evidence-based beta-blockers, angiotensin receptor neprilysin inhibitors (ARNIs), angiotensin receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, mineralocorticoid receptor antagonists (MRA), and sodium-glucose cotransporter 2 inhibitors (SGLT2is), particularly in patients with obesity or T2DM [53]