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1 GLP-1 RAs have demonstrated a benefit in patients with diabetes by stimulating glucose-induced insulin release, inhibiting the secretion of glucagon, and suppressing appetite
The third limitation is that there may be the potential for numerous indirect effects or confounding
Wegovy, which seemed to sail smoothly, hit a snag after announcing follow-up data in May 2022
Some patients experience noticeable appetite suppression and early weight loss within weeks, while others require several months to see significant changes
Kline face-to-face via secure video
Risks associated with mass-produced compounded GLP-1s Although the FDA has declared that the supply shortage is resolved, some companies continue to mass produce compounded versions of GLP-1s, claiming that the drugs are personalized for patient needs by altering the method of delivery (e.g., gummy, injection, spray) or adding unnecessary and unproven ingredients like B12 and glycine
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