There's no universal answer
Guo Q, et al
The mechanism provides a likely explanation for the increased prevalence of cholesterol gallstones in females
In a recent study that examined total isothiocyanate content in 73 samples from nine types of raw cruciferous vegetables commonly consumed in the US (namely broccoli, cabbage, cauliflower, Brussels sprout, kale, collard green, mustard green, and turnip greens), an average yield of 16.2 mol/100 g wet weight was reported, with a 41-fold difference of isothiocyanate yield across the vegetables
This timing allows for optimal absorption without interference from food
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