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In parallel, a phase 4 RCT (NCT07111494) will compare GLP-1RAs with nutritional counseling in PsA patients with obesity and T2DM, incorporating both clinical and patient-reported outcomes

Recent Mergers & Acquisitions (M & A) 2025-2026: Mar 2026: BioMarin Pharmaceutical agreed to acquire rare disease biotech Amicus Therapeutics for $4.8B, strengthening metabolic & rare disease franchise overlap with diabetes-associated disorders Mar 2026: Sanofi entered $2.2B acquisition deal for Dynavax Technologies to expand vaccine and immunometabolic pipeline supporting diabetes-comorbidity therapeutics Jan 2026: Eli Lilly and Company announced acquisition of Ventyx Biosciences for $1.2B, expanding cardiometabolic and diabetes-related pipeline into immunology-linked therapies 2026 (closed/announced): Merck & Co

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Safety data comes only from separate use of each compound

For successful transdermal delivery, compounds must overcome several challenges: 1

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