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10.1155/2018/9185368 264 YuanP.YangT.MuJ.ZhaoJ.YangY.YanZ.et al

Increased CD13 expression reduces reactive oxygen species, promoting survival of liver cancer stem cells via an epithelial-mesenchymal transition-like phenomenon

They chose this enzyme because adult worms need to make antioxidants (chemicals that prevent oxygen from damaging cells) to protect themselves against the human immune response

VEGF is up-regulated during hypoxia and orchestrate blood vessel formation mainly via activation of VEGF receptor-2 (VEGFR-2) expressed by endothelial cells [120]