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Semaglutide, a medication classified as a GLP-1 receptor agonist and used to treat obesity, is associated with a notable loss of lean body mass

This is one of the clinical decisions where I will be firm with the patient and explain why

This means that Semaglutide provides the same effect as this natural substance (GLP-1) in our bodies

Understanding the level of weight loss achieved with each can help guide medication selection

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At baseline, mean body weight was 79.6 kg, significantly greater reductions in body weight were observed for oral semaglutide 7 mg (-1.2 kg) and 14 mg (-2.0 kg) than for placebo (-0.8 kg) at week 26 but not for oral semaglutide 3 mg (-0.0 kg)