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Kyn/Trp values above the control median were observed among 83% of patients and 80% of asymptomatic carriers (Table 2) compared to the median of healthy controls

Over 26 weeks, including a dose-escalation period of up to 6 weeks, researchers observed mean percentage weight reductions of 6.0% to 10.8% across the cagrilintide dose groups compared to just 3.0% with placebo

Sequential switching is a safer alternative if monotherapy plateaus or causes intolerance

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