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Esophageal surgery is generally avoided whenever possible, because it is difficult and invasive (requiring a thoracotomy), with risk of serious complications, such as failure of anastomosis, necrosis, and stricture formation

Two key enzymes that control histone modifications are histone methyltransferases and deacetylases, and dysregulation of these enzymes may play a role in HT pathogenesis (Pu And Zhang 2024)

PMID: 15748676

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(Source 7) One small study showed that drinking 5 cups of coffee per day increased glutathione levels by 16% compared to a control group