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The glutathione peroxidase, which is responsible for protecting lipids and proteins from oxidation, is regulated by the essential trace metal element Selenium (Se) [124]

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Thus, the formation of the dehydro-alanine glutathione species (that observed at m / z 272 in the spectra of glutathione-bound metals) is a key to the possible explanation of the ability of metals such as lead and cadmium to generate oxidative stress in cells without the necessity that the electrochemically silent metal itself change its oxidation state

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Restoring gut microbiota balance may enhance selenium absorption and utilization, thereby supporting thyroid hormone synthesis and mitigating inflammatory responses