While claims now encompass Saxenda, the MDL remains focused on gastrointestinal injuries such as gastroparesis, small bowel obstruction, and gallbladder complications
AST and ALT are particularly sensitive to changes in liver health, with higher levels often being a red flag for clinicians
The American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) recommend an A1C level of 6.5% or less for diabetics without concurrent serious illness and low hypoglycemia risk, and a level of about 6.5% - 7% for those with concurrent illnesses or increased hypoglycemia risk (Garber 2020)
and (2) to perform an agent-level NMA comparing tirzepatide with individual GLP-1RAs, including albiglutide, dulaglutide, efpeglenatide, exenatide, liraglutide, lixisenatide, and semaglutide
Science 359:10971098
The current self-pay pricing breaks down as follows: 2.5 mg dose: $349 per month 5 mg dose: $499 per month 7.5 mg and 10 mg single-dose vials: $499 per month 12.5 mg and 15 mg: $499 per month through LillyDirect With commercial insurance and the Eli Lilly Savings Card, qualifying patients can access tirzepatide for as low as $25 per month
