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Chemotherapy of brain tumors has been mainly limited by a lack of effective methods of drug delivery, due to the blood-brain barrier (BBB) that prevents many drugs from reaching the cancer mass (4, 5)

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Compounded semaglutide and tirzepatide are prepared by licensed 503A compounding pharmacies based on individual, patient-specific prescriptions

The demographic and anthropometrical characteristics of the participants are presented in Table 1

Several approaches including epigenetics, postmortem studies, and measurement of GABA level in cerebrospinal fluid and plasma have been used to unravel the role of the GABA system in the pathophysiology of psychiatric disorders (131)

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