Other important adverse effects to be aware of include: Pancreatitis : If suspected (severe, persistent abdominal pain that may radiate to the back), stop taking Rybelsus immediately and seek urgent medical attention Gallbladder disease : Including gallstones and inflammation of the gallbladder (cholecystitis) Diabetic retinopathy complications : Particularly in patients with pre-existing retinopathy, especially those on insulin Dehydration and acute kidney injury : From persistent vomiting or diarrhoea Whilst there is ongoing surveillance regarding a potential link between GLP-1 receptor agonists and thyroid tumours, there is no established causal relationship in humans, though the medication carries precautionary labelling based on animal studies
10.1016/j.regpep.2011.12.006
Chen, H., et al
After a 4-hour fast, mice were intraperitoneally injected with 2 g/kg body weight arginine in sterile 0.9% saline
Since side effect profiles aren't fully defined in long-term human use, consulting with a physician is essential to ensure your safety
Cells were subsequently washed and imaged in RMPI-1640 media without phenol red (Gibco) using a 100x/1.4 NA oil objective on a Leica Stellaris 8 STED FALCON microscope from the Imperial Facility for Ligh Microscopy (FILM), using previously described confocal settings (14)
