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The research demonstrated a specific molecular mechanism - P9 binding to intercellular adhesion molecule 2 (ICAM-2) on intestinal L-cells - triggering GLP-1 release

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Costa-Almeida, R., Calejo, I

A peptide with reduced acidity was designed for increased cell permeability The p53 TAD2 sequence exhibited a highly negative charge, whereas the p53 binding interface of the FOXO4 FHD contains several positively charged residues

[DOI] [PubMed] [Google Scholar] 71.Rimbach G., Moehring J., Huebbe P., Lodge J.K