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Notably, glutamine can be converted to -ketoglutarate (KG), a key intermediate in TCA cycle, through a process called glutamine anaplerosis

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"As the respiratory organelle, mitochondria produces energy," Birsoy notes

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10.1007/BF02263605

one study found B12 supplementation (combined with folate) reduced homocysteine by 36%.(6) Tip: It is always a good idea to take Vitamin B12 as part of a whole B-vitamin complex