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(128) found that silicone oil (SiO) inhibits the proliferation of HTMCs by upregulating fibrosis-related markers and elevating ferroptosis levels through the ROS/NOX4/Smad3 signaling axis

Gut-flora-dependent metabolite trimethylamine-N-oxide promotes atherosclerosis-associated inflammation responses by indirect ROS stimulation and signaling involving AMPK and SIRT1

Retatrutide at 12 mg produced 24.2% body weight loss in phase 2 trials, the highest of any single-agent compound tested

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For example, atherosclerotic cardiovascular disease, which includes conditions such as stroke and heart attack, involves high levels of blood sugar