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0.25 mg once daily for 3 to 4 weeks 0.25 to 0.5 mg once daily for 4 to 6 weeks 0.5 mg split into two daily doses for 6 to 8 weeks Subcutaneous, 1 to 2 inches from injury location Conservative vs

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1 IDH1 inhibitor or knockdown decreases resistance to DNA damaging agents in CCNE1-driven and MYC-driven models

Although a truly clone-directed therapy might become feasible for autoimmune diseases with a single autoantigen using antigen-specific CAR-T cells, this seems unlikely for SLE with its numerous and diverse autoantigens

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