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At the highest dose of each drug, 88% of subjects experienced any adverse side effects with semaglutide, whereas 64% of subjects on tirzepatide had side effects

Some patients experience side effects with semaglutide that resolve when switching to tirzepatide, or vice versa, due to differences in how each medication engages your digestive and endocrine systems

One way this could be achieved would be if different hindbrain GLP-1-producing neurons have divergent projection targets and a different set of inputs

The regulator's 180-day review timeline for generic applications means approvals could begin appearing in the coming months

Semaglutide should be stored in the refrigerator until use