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Randomization: AOD-9604 at doses 0.25, 0.5, 1.0 mg daily SC vs placebo

The risks of microdosing are significant and multifaceted: Therapeutic inefficacy : Sub-therapeutic doses may fail to achieve meaningful improvements in glycaemic control or weight management, potentially delaying appropriate treatment and allowing disease progression

Long-term metformin use for Alzheimer's disease prevention

When GLP-1 reaches the pancreas, it binds to the GLP-1 receptors (GLP-1R) expressed on pancreatic cells, stimulating insulin release

Mitrofanova, A., Merscher, S

Treatments or hormone therapy dont work the same for every individual